Τhe Eliopoulos lab uncovers a novel function of TPL2 kinase as negative regulator of lung carcinogenesis.
Publication: The Eliopoulos lab in collaboration with the Liloglou team at the University of Liverpool uncovered a novel function of TPL2 kinase as suppressor of lung carcinogenesis. |
The Eliopoulos lab in collaboration with the Liloglou team at the University of Liverpool uncovered a novel function of the TPL2 kinase as suppressor of lung carcinogenesis. By combining genomic analyses of human tumors with cell and animal model systems, Gkirtzimanaki, Gkouskou et al report in PNAS the operation of multiple genetic and epigenetic mechanisms which lead to loss of TPL2 expression in lung tumors and link TPL2 to key pathways regulating the apoptosis barrier to cancer.
TPL2 kinase is a suppressor of lung carcinogenesis ... |
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Designed by: George Savakis for Virtual Medical Lab (Faculty of Medicine - Univercity of Crete)